Computer-Aided Drug Design (CADD)
Free Download Udemy Computer-Aided Drug Design (CADD). With the help of this course you can CADD Online Certification Program.
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What will I need?
- A basic level of knowledge about various concepts involved in Chemistry and biotechnology is required.
Is this course right for me?
- The courses are designed to suit graduates, postgraduates, teaching, and industry professionals along with research enthusiasts.
What am I going to learn?
- Module 1: Introduction to CADD
- Module 2: Ligand-based drug design (Pharmacophore design)
- Module 3: Structure-based drug design (target-ligand docking)
- Module 4: Significance and limitations of CADD in Drug Discovery and Development
- Module 5: Case study
Coupon :- CADD13 used for 13$ price .
Computer-Aided drug design(CADD) is an amazing approach that applies computational methods to discover, develop, and analyze drugs and similar biologically active molecules. Over the past few years, CADD has been involved in some of the most significant contributions in the discovery of new drugs, active molecules, etc. One cannot ignore the role of Computer-aided drug design in the vaccine development for the COVID 19 virus.
CADD aims to equip you with the knowledge about drug discovery, Ligand-based drug design, structure-based drug design, its importance, and limitations. Each lecture in the courses covers the topics at a perfect pace in an elaborate manner.
What this course covers:
Module 1: Introduction to CADD
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Overview of the process of drug discovery
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Introduction to Bioinformatics and Understanding Genomics, Proteomics and CADD
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Databases
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Sequence-Based Search Tool [BLAST]
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Factors affecting drug discovery
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Types of CADD
Module 2: Ligand-based drug design (Pharmacophore design)
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Pharmacophore Modelling
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QSAR analysis
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Similarity search/clustering
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R-group decomposition
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Matched pair analysis
Module 3: Structure-based drug design (target-ligand docking)
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Introduction to Structure-based Drug Design and process layout of Docking
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Data mining, literature study, and acquisition of target structure
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Comparative modeling of protein (Homology modeling)
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Active site/ Pocket identification –MetaPocket,CastP,Active site identification using PyMol
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Protein and ligand preparation
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Docking analysis (based on binding energy, Hydrogen bond interactions, electrostatic interactions, hydrophobic interactions, etc.)
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Approaches of Structure-based drug design: Structure-based virtual high-throughput screening, Fragment-based lead discovery, In silico structure-based lead optimization, ADMET modeling
Module 4: Significance and limitations of CADD in Drug Discovery and Development
Module 5: Case study
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